options nodate pagesize=54 linesize=80; /* Read in the input file */ data ex0306; * infile '../../../data/biostat/ex0306.dat'; infile 'C:\biostat\data\ex0306.dat'; input subject src irc; src_irc = src-irc; run; /* Obtain Wilcoxon Signed rank test and paired t test, where src_irc is the difference in auc under the 2 formulations (sustained release - immediate release) */ /* Note the W statistic for the Signed Rank test is (T+)-average(T+,T-) */ proc univariate; var src_irc; run; quit;