If you're driving, it's useful to know that with just a few exceptions Gainesville is laid out on a grid system. Avenues, Places, Road, and Lanes (just remember APRiL) run east-west, while most everything else (streets for example) runs north and south. University Avenue divides North from South, and Main Street divides East from West.
To get to the conference hotels, here's what you should do:
To continue to the REITZ UNION:
NEWSFLASH: The circle at the end of the driveway into the Reitz Union Hotel is presently blocked by contruction. If you're being dropped off, just get out here and make your way around the fence. If you're driving, park in the lot to the right (there may be some metered spots) and walk up the stairs to the Union. Again, you should get a parking pass from the clerk when you check in.
You can visit
http://www.ifas.ufl.edu/www/campusmap
to see a campus map. The last "major" intersection in the upper right
corner of the map is the intersection of University Ave and West 13th
St. (location of the Holiday Inn). If you enter "Reitz" in the Map
Search box it will show you where Reitz Union is. You can click to
zoom in. Of course you can also find Dauer Hall, University
Auditorium, and Griffin-Floyd Hall in the same way.