Devan V. Mehrotra
Ph.D.
Merck Research Labs
Clinical Biostatistics, UN-A102
785 Jolly Rd, Bldg C
Blue Bell, PA 19422
E-mail Address: devan_mehrotra@merck.com
Web Address: None
Phone: (610) 397-2621
Fax: (610) 397-7105
Address: Merck Research Labs
Clinical Biostatistics, UN-A102
785 Jolly Rd, Bldg C
Blue Bell, PA 19422

Title: Robust Analysis of Repeated Measures Experiments
Duration: 1 hour
Audience: Graduate students and faculty
Abstract: The iterative restricted maximum likelihood (REML) method is popularly used to analyze data from repeated measures or "split-plot" experiments. While REML has attractive large sample properties for normal data, it can perform poorly in the presence of "outliers" or systematic departures from normality. In this talk, a non-iterative robust alternative to REML, called the RAVE method, will be presented, and illustrated using data from a 2x2 crossover study.
Honorarium: None